Objective: Gynecological cancer is one of the deadliest types of cancer in women. Chemotherapy is one of the medical treatment options to kill cancer cells that spread throughout all parts of the body. The aim of this study was to identify the effect of giving "DORLAN" health education to physical and sexual problems of gynecological cancer patients during chemotherapy.

Method: A quasi- experimental design was used. A sample of 94 women with gynecological cancer who were undergoing chemotherapy divided into 2 groups: the intervention group that received DORLAN health education and the intervention group that received routine health education from the hospital. This research was conducted in the chemotherapy room at two cancer referral hospitals in Jakarta. Data collection were perfomed using demographic data questionnaires, a FACT-G questionnaire, a Sexual Satisfaction Scale for Women (SSS-W) questionnaire, and a Multidimensional Scale of Perceived Social Support (MSPSS) questionnaire.

Result: The results of this study showed that the "DORLAN" health education package had an influence on the physical and sexual problems of gynecological cancer patients who were undergoing chemotherapy.

Conclusion: “DORLAN” health education package could empower nurses serving in the chemotherapy room and should be given before chemotherapy to prevent physical and sexual problems during chemotherapy.

Keywords: Gynecological cancer Chemotherapy, Side Effects Chemotherapy, Health Education