Hallucinations and self-care deficits are positive and negative symptoms of schizophrenia. Nursing care can be given to improve the client's ability to solve problems. The objectives of this study is to determine the effect of nursing nurses' actions, family psychoeducation, behavioral therapy, cadre assistance, and medical services on clients with hallucinations and self-care deficits. Further, the final design of this study is a case series with 6 clients. The activity consisted of 16 meetings; 7 meetings with nurses, 4 meetings with cadres, and 5 meetings with medical services. The instruments used were instruments of signs and symptoms as well as hallucinations and self-care deficits. The results show that clients who get nursing action, family psychoeducation, behavioral therapy, cadre assistance, and medical services experience a decrease in signs and symptoms as well as an increase in their ability compared to clients who only get nursing action, family psychoeducation, behavioral therapy, and medical service, and clients who only get nursing actions, family psychoeducation, and behavioral therapy. This study recommends the importance of nursing intervention, family psychoeducation, behavioral therapy, as well as cadre assistance and medical services for clients and with hallucinations self-care deficits.