Background: The proportion of elderly people in big cities of developing countries is rapidly increasing during the age of rampant urbanization. This being followed by a sustained rise of illnesses, especially mental health issues. Geriatric depression is common among elderly. However, the disorder remains under-diagnosed and under-treated. We undertook a systematic review of International literature to identify essential factors influencing quality of life in elderly depression.

Method: A systematic review of studies written in English and publish between January 2015-December 2018. Data source were Ebsco, Proquest, Scince Direct, Willey Online Library, Scopus, and grey literature in Indonesia. After screening articles to ensure that reported on a key word and removing duplicates, eligible papers were appraised and evaluated.

Result: Twenty five studies were eligible for inclusion in the review from 993 screening process records identified through database searching, duplicates removed, and full text articles excluded with reasons. Essential factors influencing in quality of life in elderly depression: Religious belief, satisfaction regarding quality of life, suffering from more chronic disease, experiencing negative event, lack of abiity to take self-care.

Conclusion:Screening for early depression, joining social programming, and participating in physical activities may improve the mental health life and quality of life of the elderly.

Keyword: elderly, depression, quality of  life.