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Background: Children admitted to the Pediatric Intensive Care Unit (PICU) are at risk for pressure injury due to immobility and the challenge of positioning medical devices. However, a comprehensive instrument to assess pressure injury risk is still finite. This study aimed to test the validity and reliability of the Braden QD Scale for pediatric patients who were admitted to a PICU. Methods: Fifty-one pediatric patients below age 18 who had been bedridden for at least 24 hours were engaged through a consecutive sampling method. Pearson correlation coefficients and Cronbach’s alpha (α) were applied to assess validity and reliability (P < 0.05) Results: Assessments made by using the Braden QD Scale revealed that 88.2% of patients were at risk for a pressure injury (54.9% of men, 37.3% of patients aged one month to one year). The validity test results of the Braden QD Scale ranged between 0.532 and 0.833, while the Braden Q Scale ranged between 0.528 and 0.804. The reliability test results of the Braden QD Scale ranged between 0.756 and 0.834, while the Braden Q Scale ranged between 0.724 and 0.754. Conclusion: In general, the study finding suggests that the Braden QD Scale is a valid and reliable instrument for predicting pressure injury risk in pediatric patients under age 18 with immobility and medical devices. Nurses may employ this tool to assess pressure injury risk in pediatric patients.