The prevalence of occupational accident in Indonesia is still high. One of causes of the accidents is the high level of work-caused fatigue from work shift factor. This study aims to determine relation between work shift and fatigue level among workers at PT STI Tbk Cikupa, Tangerang. The desaign used with cross-sectional approach. Total sampling technique was applied with the total 80 workers respondents. Data analysis used univariate and bivariate. This study showed the relation between work shift and work-caused fatigue was 0,235 (p value >0,05). There was no significant relation between work shifts with work-caused fatigue in workers at PT STI Tbk Cikupa, Tangerang. This study recommends the companies to attention to middle adult workers, causes as workers with middle adult will feel tired quickly. Workers with level middle adult are better placed on part with workload is not too high. And this study also recommends the workers with shifts or non-shifts have the rest period of 30 minutes after working 4 hours, use the rest time to add back body's energy

Keywords : fatigue level, work shift