Health should not be only physically, mentally, and socially, but also emotionally, spiritually, societal, sensual, and sexually. Various workplace hazards and risks can lead to occupational or work-related diseases and accidents. One of the work-related accident problems that should be paid more attention is the accident related to fatigue. The threatening of fatigue leads to increasing accidents due to fatigue in the workplace. PT. X is a coal mining company in Indonesia. There are 69 cases of fatigue related accidents within 4 years (2015-2018). The purpose of this study was to know the risk factors of fatigue that lead to accidents. This is a descriptive study based on accident case reports using a literature study approach. The accident related to fatigue in PT. X more happens to workers with a 2 shift work pattern of 64% compared with 3 shift work pattern of 36%, most often occurs at 04:00-08.00 AM, 2nd shift and 3rd shift accounted for 52% and 30% accident, with the trigger fatigue due to lack of downtime and embarrassment to reveal that workers experience a burnout of 48% and 32% respectively.