Evaluation of the use of PPI needs to be done perceiving the high use of Proton Pump Inhibitor (PPI) and likely impacts from inappropriate use of PPI. The aim of this study was to evaluate the use of PPI on inpatients at Gatot Soebroto Army Center Hospital. The study design was observational analytic descriptive with prospective data collection method based on prescription and medical record. The sample was data of entire adult inpatients with national health insurance held by Health Social Insurance Organizing Board (BPJS Kesehatan) who used PPI at internal disease department of RSPAD. PPI use was evaluated based on rationality and therapy effectiveness. Analysis carried out on 153 PPI therapies of 91 patients. The percentages of PPI therapies with appropriate indication was 77,78%, appropriate drug selection was 77,78%, appropriate patient condition assessment was 98,69%, appropriate dose was 4,58%, appropriate therapy duration was 66,01%, and therapy effectiveness was 86,27%. Only 3,92% PPI therapies were rational regarding all the appropriate criterias fulfillness.

Keywords: Proton pump inhibitor