E-government has been proved to play an important role in improving government services quality by promoting efficiency and effectiveness in service delivery as well as increasing transparency and accountability in public administration which further may contribute to the eradication of corruption in many countries in the world.  This study aims to figure out the potential role of e-government implementation in reducing the corruption level in Southeast Asia (ASEAN) countries using perceived level of Corruption Perception Index, e-government development index, and e-participation index. Empirical findings show that e-government has the potential to eradicate corruption within public service in ASEAN countries, whereas e-participation has positive relation with CPI, yet insignificant. This paper recommends developing countries in Southeast Asia to implement and develop e-government as anti-corruption tool to mitigate corruption which would potentially be benefited in increasing economic growth and reaching better development.