Universitas Indonesia Conferences, Asian Federation for Pharmaceutical Sciences (AFPS) 2019

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FREEZE DRYING OF NATURAL DEEP EUTECTIC SOLVENT EXTRACT OF GREEN COFFEE BEANS (Coffea canephora Pierre Ex. A. Froehner)
Rensa Alsya Fitri, Tia Andriani Lestari, Yunita Sari, Sutriyo Sutriyo, Abdul Mun'im

Last modified: 2019-07-13

Abstract


NADES (Natural Deep Eutectic Solvent) as green solvent had succeeded in attracting caffeine and chlorogenic acid from green coffee beans. NADES has very low eutectic points so that freeze-drying is suitable as drying method. However, freeze-dried product are hygroscopic so it can cause stickiness. This study aims to produce dried NADES extract of green coffee beans. In pretreatment of freeze drying, addition of  water was needed as antisolvent and excipients (maltodextrin, Arabic gum, and its combination at 25%, 30%, and 35% and Aerosil® at 1%, 2%, and 3%) were added to improve the quality of dried extract. The results of the freeze-dried extract had dried successfully that the increasing excipients improve the physical qualities and reducing stickiness.