Last modified: 2019-07-13
Abstract
Prescription Pattern of Anti-Peptic Ulcer Drugs at a Hospital in Cimahi
1) Linda P. Suherman, 1)Sri Wahyuningsih, 2)Nisa Haraya Nur Fitriani, 1)Vina Septiani, 1)Alfi Nurul Islamiyah, 1)Diani Desti Fuji Astuti
1) Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Jenderal Achmad Yani, West Java, Indonesia
2) Pharmacy Installation of Cibabat Regional General Hospital, Cimahi, West Java, Indonesia
Corresponding e-mail : lindapsuherman@gmail.com
Background: Peptic ulcer is a disease defined by disturbances in the upper gastrointestinal tract caused by excessive secretion of acid and pepsin by the gastric mucosa. Cigarettes,alcoholic drinks, NSAIDs, and Helicobacter pylory are some of the factors that can causeulcer disease.Objective: The purpose of this study was to determine the description and rationality of drug use in patients with peptic ulcer.
Method: This study was conducted in a descriptive with a cross sectional approach at one of Hospital in Cimahi. The population study was peptic ulcer inpatient in the periode of 2017 to 2018 wich was in accordance with the inclusion criteria.. Data was obtained from patient medical record and the sampling method was total sampling.
Result: The results of the analysis of the use of peptic ulcer drugs at one of Hospital in Cimahi in 2017-2018 found that peptic ulcer patients were more commonly found in female patients by 58%, with a maximum age of 46-65 years equal to 58%. Anti-ulcer therapy that were prescribed included proton pump inhibitor (pantoprazole, lansoprazole), H2 receptor antagonist (ranitidine), and mucose protective (sucralfate). Most patients were prescribed a combination of two anti-ulcer therapy (60.8%), as many as 36.3% were prescribed anti-ulcer monotherapy, and only 2.9% of patients were prescribed a combintion of three anti-ulcer therapy that included pantoprazole, ranitidine, and sucralfate.Conclusion: Based on the results of the research that has been done, it can be concluded that the most single-use anti-ulcer drug is pantoprazol at 23.2% and combination of two Pantoprazol + Sucralfate drugs at 53.6%. Keywords : Anti-peptic ulcer, Prescription, Hospital