Background: Patient compliance is an important factor to achieve treatment outcomes, especially for long term medication such as in diabetes mellitus. Objective: The purpose of This study is to provide an overview of patient compliance at general hospital in Maros South Sulawesi. Materials and Methods: Thirty participants who meet criteria were enrolled in this study. Data were obtained prospectively. Participants were interviewed using MMAS-8 (Morisky Medication Adherence Scale-8) questionnaire. Results: The results showed that Low level compliance were 30%, Moderate  43,3%, and high 23,67%. Age and duration of Diabetes Mellitus Type 2 were given significant result between compliance level (p<0,05). Other factors like Gender, Education level, Occupation, Diet status, Activity, comorbidity, and drug regimen were no influence in compliance (p>0,05)  Conclusion: The majority compliance among participant were moderate (43,3%). Age and Duration of DMT2 were the factor influenced in compliance.

Key words: Compliance, Diabetes Mellitus type 2, MMAS-8